Nikolaos Kalavrezos

CV

Nicholas Kalavrezos is a Senior Head and Neck Reconstructive Surgeon in the Head and Neck Centre at University College London Hospital with a background in Oral and Maxillo-Facial surgery.

Nicholas is also the Lead Head and Neck Sarcoma Surgeon for the London Sarcoma Service. His clinical practice includes ablative and reconstructive surgery for the head and neck with a special interest in bone sarcomas and functional outcomes following reconstructive surgery. His clinical practice also includes surgical treatment of salivary gland and  thyroid neoplasias.

Nicholas’ research interests include applications of “tissue engineering” in head & neck reconstruction. Nicholas is a founding member of the “Centre for Reconstructive Surgery” at University College London and holds a Senior Lecturer post at the same Institution. He is also a member of the “Face Transplant Group” based at Royal Free Hospital aiming to perform the first face transplant in the UK.

He has joint research projects in the Nanotechnology Lab of UCL on “tissue engineered bio-scaffolding” aiming to replace defects of the head and neck with tissue– engineered based micro-vascular flap reconstruction. The FORTE flap is a paradigm to this direction.
Nicholas lectures regularly at national and international meetings and is the President of the European Association for Cranio-Maxillofacial Surgery (EACMFS).

 

Experience

CONSULTANT MAXILLOFACIAL / HEAD & NECK SURGEON   04/2002 – present

University College London Hospitals – UK

Clinical Lead  2007-2018

 

CONSULTANT HEAD & NECK SURGEON  04/2002 – present

London Sarcoma Service – London, UK

Clinical Lead Head & Neck Sarcoma Surgery  2007    –   present

 

Core Qualifications

Medical School of University of Patras, Greece (1993)

Dental School of University of Athens, Greece (1986)

 

Education

Royal College of Surgeons – Edinburgh | Intercollegiate Fellowship in Oral & Maxillofacial Surgery FRCS (OMFS) – 2001

Royal College of Surgeons – Dublin, Ireland, Ireland | Fellowship of the Faculty of Dentistry- FFD FRSCI – 1999

Royal College of Surgeons – Edinburgh | Fellowship FRCS (Ed) – 1998

University of Zurich – Zurich, CH | Dr Med Dent  – 1998

Long term results after treatment of frontal sinus fractures:

Clinical and radiological aspects

University of Zurich (USZ) – Zurich, CH | Doctor of Medicine  – 1995

Bone scanning for the evaluation of carcinomatous invasion of the mandible

 

Accomplishments

Development of the Head & Neck Surgical Services in Sarcomas at UCLH

Largest head & neck sarcoma surgery series in Europe

Ethical Approval and Clinical Application for Pre-fabrication of Osseo-Mucosal Free Flaps in Head & Neck Reconstruction

Pre-fabrication of osseo-mucosal flaps combining free vascularised fibula bone flap and artificial dermis (INTEGRA) in conjunction with osseo-integrated dental implants for immediate use

Lipo-transfer for Fibrosis Reversal in Head & Neck post-radiotherapy patients Joint clinic with Prof Peter Butler (Plastic Surgery) for management of post-irradiation secondary problems

Development of European Fellowship in Head & Neck Surgery UCLH

• Trends and Challenges in Flap-Based Implant Rehabilitation in Major Head & Neck Oncology
• Long-term outcomes following FORTE (Functional Oral Rehabilitation Tissue Engineered) flap: applications and long-term outcomes

Abstract

Free flap reconstruction of a facial bone defect is considered the “gold-standard” in head & neck reconstruction. The inclusion of dental implants adds the benefit of a complete dental rehabilitation -at least- when the defect is limited to the oral cavity.

There are 2 major concepts that we will develop in this comprehensive presentation:

1. The use of the sub-unit concept in flap-implant based reconstruction and rehabilitation for the oral cavity and the mid-face / orbit alike.
2. The use of a pre-fabricated with mucosa-like and implants fibula flap (FORTE flap) for patients with oral pre-malignant / low grade malignant conditions and severe fibro-osseous lesions in need of segmental resection of the mandible.

 

A systemic approach to defect reconstruction/ rehabilitation will be presented and the concept of the FORTE flap will be developed.